Neuroimaging Predictors of Bariatric Surgical Outcome

This study is looking to determine whether weight loss following bariatric surgery is related to differences in the way the brain functions.

This is done by taking pictures of your brain using an MRI machine while you complete several tasks related to food. This project aims to better understand why there is so much variation in weight loss after bariatric surgery. We are currently recruiting comparison participants who are not undergoing weight loss surgery. Our staff will answer any questions or concerns you may have and can help determine eligibility for this study. 

Researchers on this team:

Who can participate?

Adults, ages 18 – 60, who have a body mass index (BMI) over 35. In addition, participants should be:

  • Not currently taking appetite suppressant medications
  • Comfortable lying flat on their back for up to two hours at a time

Because of the use of MRI, anyone who has a permanent metal object (such as a pacemaker) inside his or her body cannot participate.

What will I do?

Qualified participants will complete:

  • An interview with trained staff
  • Neuropsychological testing, which consists of tests that measure cognitive abilities
  • Questionnaires about a variety of things, including the participant’s eating behaviors
  • A safe and non-invasive fMRI scan
  • Activity monitoring using a lightweight accelerometer

These activities take place over three study visits: a 5 – 6 hour screening visit and a 3 hour MRI visit at baseline, and a 5 – 6 hour follow-up visit after 1 year. All information is kept strictly confidential, with one exception. Staff will tell another health professional if they learn that the participant is in any danger of physically harming him/herself or others.

What do I get out of this?

Participants will help us understand how brain function is related to weight loss following bariatric surgery. Participants are given $20 an hour for the time that they participate as well as additional monetary incentives for completing different tasks. While our research staff cannot provide treatment, we can refer anyone who desires follow-up assessments or treatment to Hartford Healthcare staff who can assist you.

Contact us to participate:

Olin Neuropsychiatry Research Center